{"id":100931,"date":"2025-10-13T10:46:08","date_gmt":"2025-10-13T14:46:08","guid":{"rendered":"https:\/\/romanticany.com\/?p=100931"},"modified":"2025-10-13T10:46:10","modified_gmt":"2025-10-13T14:46:10","slug":"investigadores-descubren-que-la-geometria-del-cerebro-puede-predecir-el-riesgo-de-alzheimer-anos-antes-de-los-sintomas","status":"publish","type":"post","link":"https:\/\/romanticany.com\/?p=100931","title":{"rendered":"\u00abInvestigadores descubren que la geometr\u00eda del cerebro puede predecir el riesgo de Alzheimer a\u00f1os antes de los s\u00edntomas\u00bb"},"content":{"rendered":"\n<p>Un equipo de cient\u00edficos internacionales, con participaci\u00f3n destacada de la <strong>Universidad de California en Irvine<\/strong>, ha descubierto que <strong>los cambios en la forma del cerebro<\/strong> podr\u00edan ser un <strong>indicador temprano<\/strong> del desarrollo de demencia, incluso antes de que aparezcan los s\u00edntomas cl\u00ednicos. El estudio, publicado en <strong>Nature Communications<\/strong>, analiz\u00f3 m\u00e1s de <strong>2,600 im\u00e1genes cerebrales<\/strong> de personas entre <strong>30 y 97 a\u00f1os<\/strong>, revelando que ciertas <strong>alteraciones geom\u00e9tricas<\/strong> en el cerebro est\u00e1n relacionadas con el <strong>deterioro cognitivo<\/strong> y podr\u00edan servir para predecir el riesgo de enfermedades como el <strong>Alzheimer<\/strong>.<\/p>\n\n\n\n<p>Los investigadores observaron que, con el avance de la edad, <strong>algunas \u00e1reas del cerebro se expanden<\/strong>, mientras que otras <strong>se reducen<\/strong>. Las regiones <strong>inferiores y frontales<\/strong> tend\u00edan a aumentar de tama\u00f1o, mientras que las <strong>superiores y posteriores<\/strong> mostraban una tendencia a la compresi\u00f3n. Estas variaciones eran <strong>m\u00e1s marcadas<\/strong> en adultos mayores con <strong>problemas de memoria y otras funciones cognitivas<\/strong>, lo que sugiere que podr\u00edan ser un <strong>marcador temprano<\/strong> de enfermedades neurodegenerativas.<\/p>\n\n\n\n<p>Uno de los hallazgos m\u00e1s relevantes del estudio se centr\u00f3 en la <strong>corteza entorrinal<\/strong>, una regi\u00f3n clave para la memoria ubicada en el <strong>l\u00f3bulo temporal medial<\/strong>. Esta \u00e1rea es una de las primeras en acumular la <strong>prote\u00edna tau<\/strong>, asociada con el <strong>Alzheimer<\/strong>. Seg\u00fan el cient\u00edfico <strong>Michael Yassa<\/strong>, las deformaciones en la estructura cerebral podr\u00edan <strong>desplazar la corteza entorrinal hacia la base del cr\u00e1neo<\/strong>, lo que acelerar\u00eda su <strong>degeneraci\u00f3n<\/strong>. <em>\u00abEsto podr\u00eda explicar por qu\u00e9 esta regi\u00f3n es el punto de origen de la patolog\u00eda del Alzheimer\u00bb<\/em>, se\u00f1al\u00f3 Yassa, destacando la importancia de este descubrimiento para entender los <strong>mecanismos iniciales<\/strong> de la enfermedad.<\/p>\n\n\n\n<p>Los resultados, <strong>verificados en dos conjuntos de datos independientes<\/strong>, respaldan la idea de que la <strong>forma del cerebro<\/strong> podr\u00eda utilizarse como un <strong>nuevo marcador biol\u00f3gico<\/strong> para detectar el riesgo de demencia en etapas tempranas. Los investigadores sugieren que este enfoque podr\u00eda no solo mejorar las <strong>estrategias de prevenci\u00f3n<\/strong>, sino tambi\u00e9n profundizar en la comprensi\u00f3n de los <strong>factores de riesgo<\/strong> durante las primeras fases de la enfermedad. Este avance abre nuevas posibilidades para el desarrollo de <strong>diagn\u00f3sticos m\u00e1s precisos<\/strong> y <strong>terapias innovadoras<\/strong> que podr\u00edan retrasar o prevenir el Alzheimer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Un equipo de cient\u00edficos internacionales, con participaci\u00f3n destacada de la Universidad de California en Irvine, ha descubierto que los cambios en la forma del cerebro podr\u00edan ser un indicador temprano del desarrollo de demencia, incluso antes de que aparezcan los s\u00edntomas cl\u00ednicos. El estudio, publicado en Nature Communications, analiz\u00f3 m\u00e1s de 2,600 im\u00e1genes cerebrales de [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":100932,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-100931","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mundo"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>&quot;Investigadores descubren que la geometr\u00eda del cerebro puede predecir el riesgo de Alzheimer a\u00f1os antes de los s\u00edntomas&quot; - Romantica NY<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/romanticany.com\/?p=100931\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"&quot;Investigadores descubren que la geometr\u00eda del cerebro puede predecir el riesgo de Alzheimer a\u00f1os antes de los s\u00edntomas&quot; - Romantica NY\" \/>\n<meta property=\"og:description\" content=\"Un equipo de cient\u00edficos internacionales, con participaci\u00f3n destacada de la Universidad de California en Irvine, ha descubierto que los cambios en la forma del cerebro podr\u00edan ser un indicador temprano del desarrollo de demencia, incluso antes de que aparezcan los s\u00edntomas cl\u00ednicos. El estudio, publicado en Nature Communications, analiz\u00f3 m\u00e1s de 2,600 im\u00e1genes cerebrales de [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/romanticany.com\/?p=100931\" \/>\n<meta property=\"og:site_name\" content=\"Romantica NY\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-13T14:46:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-10-13T14:46:10+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/romanticany.com\/wp-content\/uploads\/2025\/10\/La-forma-del-cerebro-podria-revelar-los-primeros-signos-de-esta-grave-enfermedad.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1096\" \/>\n\t<meta property=\"og:image:height\" content=\"618\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Romantica NY\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Romantica NY\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/romanticany.com\/?p=100931#article\",\"isPartOf\":{\"@id\":\"https:\/\/romanticany.com\/?p=100931\"},\"author\":{\"name\":\"Romantica NY\",\"@id\":\"https:\/\/romanticany.com\/#\/schema\/person\/be3a3ed4b2ab0af84e4dbe5c3215474c\"},\"headline\":\"\u00abInvestigadores descubren que la geometr\u00eda del cerebro puede predecir el riesgo de Alzheimer a\u00f1os antes de los s\u00edntomas\u00bb\",\"datePublished\":\"2025-10-13T14:46:08+00:00\",\"dateModified\":\"2025-10-13T14:46:10+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/romanticany.com\/?p=100931\"},\"wordCount\":404,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/romanticany.com\/#organization\"},\"image\":{\"@id\":\"https:\/\/romanticany.com\/?p=100931#primaryimage\"},\"thumbnailUrl\":\"https:\/\/romanticany.com\/wp-content\/uploads\/2025\/10\/La-forma-del-cerebro-podria-revelar-los-primeros-signos-de-esta-grave-enfermedad.jpg\",\"articleSection\":[\"Mundo\"],\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/romanticany.com\/?p=100931#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/romanticany.com\/?p=100931\",\"url\":\"https:\/\/romanticany.com\/?p=100931\",\"name\":\"\\\"Investigadores descubren que la geometr\u00eda del cerebro puede predecir el riesgo de Alzheimer a\u00f1os antes de los s\u00edntomas\\\" - 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El estudio, publicado en Nature Communications, analiz\u00f3 m\u00e1s de 2,600 im\u00e1genes cerebrales de&hellip;","_links":{"self":[{"href":"https:\/\/romanticany.com\/index.php?rest_route=\/wp\/v2\/posts\/100931","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/romanticany.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/romanticany.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/romanticany.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/romanticany.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=100931"}],"version-history":[{"count":1,"href":"https:\/\/romanticany.com\/index.php?rest_route=\/wp\/v2\/posts\/100931\/revisions"}],"predecessor-version":[{"id":100933,"href":"https:\/\/romanticany.com\/index.php?rest_route=\/wp\/v2\/posts\/100931\/revisions\/100933"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/romanticany.com\/index.php?rest_route=\/wp\/v2\/media\/100932"}],"wp:attachment":[{"href":"https:\/\/romanticany.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=100931"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/romanticany.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=100931"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/romanticany.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=100931"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}