{"id":76504,"date":"2025-05-09T11:50:16","date_gmt":"2025-05-09T15:50:16","guid":{"rendered":"https:\/\/lacomunidadysufuturo.com\/?p=76504"},"modified":"2025-05-09T11:50:16","modified_gmt":"2025-05-09T15:50:16","slug":"descubren-mecanismo-para-detectar-el-alzheimer-en-fases-tempranas","status":"publish","type":"post","link":"https:\/\/romanticany.com\/?p=76504","title":{"rendered":"Descubren Mecanismo para Detectar el Alzheimer en Fases Tempranas"},"content":{"rendered":"\n<p>Un equipo de investigadores del Centro de Biolog\u00eda Molecular Severo Ochoa, junto con la Universidad Pablo de Olavide y la VU University Amsterdam (Pa\u00edses Bajos), ha descubierto un mecanismo que provoca cambios tempranos en el cerebro mucho antes de la aparici\u00f3n de los s\u00edntomas cl\u00e1sicos del Alzheimer, lo que puede contribuir a su detecci\u00f3n precoz.<\/p>\n\n\n\n<p>El estudio, publicado en la revista &#8216;Cell Reports&#8217;, muestra que los astrocitos del cerebro pueden tener un papel \u00abclave\u00bb en el origen de esta patolog\u00eda, al producir de forma \u00abexcesiva\u00bb la prote\u00edna SFRP1, que se encarga de regular la comunicaci\u00f3n entre c\u00e9lulas durante el desarrollo cerebral.<\/p>\n\n\n\n<p>Su excesiva acumulaci\u00f3n en el cerebro adulto tiene efectos perjudiciales, y es que bloquea la actividad de la prote\u00edna ADAM10, que facilita y acelera funciones del cerebro, adem\u00e1s de ser necesaria para mantener sanas las conexiones neuronales.<\/p>\n\n\n\n<p>Este bloqueo provoca un desequilibrio que acaba deteriorando la plasticidad sin\u00e1ptica, un mecanismo \u00abesencial\u00bb para formar y consolidar recuerdos; el trabajo tambi\u00e9n muestra que el exceso de SFRP1 interfiere con la potenciaci\u00f3n sin\u00e1ptica a largo plazo, un proceso \u00abfundamental\u00bb para el aprendizaje y la memoria.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"522\" height=\"600\" src=\"https:\/\/lacomunidadysufuturo.com\/wp-content\/uploads\/2025\/05\/Promo-65-Anos.jpg\" alt=\"\" class=\"wp-image-76508\"\/><\/figure>\n\n\n\n<p>#Alzheimer #Detecci\u00f3nTemprana #SaludCerebral #Investigaci\u00f3n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Un equipo de investigadores del Centro de Biolog\u00eda Molecular Severo Ochoa, junto con la Universidad Pablo de Olavide y la VU University Amsterdam (Pa\u00edses Bajos), ha descubierto un mecanismo que provoca cambios tempranos en el cerebro mucho antes de la aparici\u00f3n de los s\u00edntomas cl\u00e1sicos del Alzheimer, lo que puede contribuir a su detecci\u00f3n precoz. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":76505,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-76504","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-salud"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Descubren Mecanismo para Detectar el Alzheimer en Fases Tempranas - Romantica NY<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/romanticany.com\/?p=76504\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Descubren Mecanismo para Detectar el Alzheimer en Fases Tempranas - Romantica NY\" \/>\n<meta property=\"og:description\" content=\"Un equipo de investigadores del Centro de Biolog\u00eda Molecular Severo Ochoa, junto con la Universidad Pablo de Olavide y la VU University Amsterdam (Pa\u00edses Bajos), ha descubierto un mecanismo que provoca cambios tempranos en el cerebro mucho antes de la aparici\u00f3n de los s\u00edntomas cl\u00e1sicos del Alzheimer, lo que puede contribuir a su detecci\u00f3n precoz. 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